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Rat M-CSF

Macrophage colony stimulating factor (M-CSF) is a hematopoietic growth factor that is widely produced by a variety of cells. M-CSF stimulates the proliferation and differentiation of hematopoietic stem cells into monocyte and macrophage cell types. M-CSF also acts through the colony stimulating factor 1 receptor (CSF1R) to modulate processes involved in immunology, bone metabolism, fertility, and pregnancy.

SKU Select size Price Buy
300-33-2ug Mini: 2 ug $67.00 + -
300-33-10ug Std.: 10 ug $168.00 + -
300-33-100ug Value: 100 ug $646.00 + -
300-33-500ug Midgi: 500 ug $3,209.00 + -
300-33-1mg Mg: 1 mg $5,347.00 + -
300-33AF-2ug Animal-Free Mini: 2 ug $73.00 + -
300-33AF-10ug Animal-Free Std.: 10 ug $184.00 + -
300-33AF-100ug Animal-Free Value: 100 ug $708.00 + -
300-33AF-500ug Animal-Free Midgi: 500 ug $3,532.00 + -
300-33AF-1mg Animal-Free Mg: 1 mg $5,882.00 + -

Alternate Names:  MGI-IM, CSF-1              Accession Number: Q8JZQ0
Description:  Macrophage colony stimulating factor (M-CSF) is a hematopoietic growth factor that is widely produced by a variety of cells. M-CSF stimulates the proliferation and differentiation of hematopoietic stem cells into monocyte and macrophage cell types. M-CSF also acts through the colony stimulating factor 1 receptor (CSF1R) to modulate processes involved in immunology, bone metabolism, fertility, and pregnancy.
Source:  Genetically modified E.coli.
Predicted MW: Dimer, 18.1/36.2 kDa (155/210 aa)
AA Sequence:  MEVSEHCSHM IGNGHLQILQ QLIDSQMETA CLIEYKFVDQ EQLDDPVCYL KKAFVLVQVI IEETMRFKDN TPNANATERL QELSMKLNSC FIKDYKEQNE ACVQTYKESP LRLLEKIKNF FNETKNFLEK DWNIFSKNCN DSLAKCSSRD VVTKP
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

NFS-60 Proliferation

ED50 ≤ 10 ng/mL (≥ 1.0 x 10^5 units/mg)

(typical ED50 is < 2 ng/mL)

Preparation and Storage

Country of Origin:  USA        Shipping:  Room temperature             
Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date                      
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

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Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 0415 Lot 0415
SDS Lot 0415 Animal-Free Lot 0415 Animal-Free
PDS Animal-Free    
SDS Animal-Free    

 

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