Mouse IL-7

 Interleukin 7 (IL-7) is a hematopoietic cytokine that is an important regulator of B and T cell development. IL-7 is secreted by bone marrow and thymic stromal cells, dendritic cells, intestinal epithelial cells, hepatocytes, and keratinocytes. IL-7 signals through the interleukin 7 receptor (IL-7R) to promote the differentiation of hematopoietic stem cells into T cells, B cells, and natural killer cells. IL-7 is also a regulator of intestinal mucosal lymphocyte proliferation. Human and mouse IL-7 show species cross-reactivity.

SKU Select size Price Buy
200-03-2ug Mini: 2 ug $63.00 + -
200-03-10ug Std.: 10 ug $158.00 + -
200-03-100ug Value: 100 ug $609.00 + -
200-03-500ug Midgi: 500 ug $3,024.00 + -
200-03-1mg Mg: 1 mg $5,040.00 + -
200-03AF-2ug Animal-Free Mini: 2 ug $69.00 + -
200-03AF-10ug Animal-Free Std.: 10 ug $174.00 + -
200-03AF-100ug Animal-Free Value: 100 ug $667.00 + -
200-03AF-500ug Animal-Free Midgi: 500 ug $3,329.00 + -
200-03AF-1mg Animal-Free Mg: 1 mg $5,544.00 + -
Alternate Names:  Lymphopoietin 1 (LP-1), pre-B cell Factor              
Accession Number: P10168
Description:  Interleukin 7 (IL-7) is a hematopoietic cytokine that is an important regulator of B and T cell development. IL-7 is secreted by bone marrow and thymic stromal cells, dendritic cells, intestinal epithelial cells, hepatocytes, and keratinocytes. IL-7 signals through the interleukin 7 receptor (IL-7R) to promote the differentiation of hematopoietic stem cells into T cells, B cells, and natural killer cells. IL-7 is also a regulator of intestinal mucosal lymphocyte proliferation. Human and mouse IL-7 show species cross-reactivity.
Source:  Genetically modified E.coli.
Predicted MW: Monomer, 15 kDa (130 aa)
AA Sequence:  MECHIKDKEG KAYESVLMIS IDELDKMTGT DSNCPNNEPN FFRKHVCDDT KEAAFLNRAA RKLKQFLKMN ISEEFNVHLL TVSQGTQTLV NCTSKEEKNV KEQKKNDACF LKRLLREIKT CWNKILKGSI
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM acetic acid

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

2E8 cell proliferation

≤1 ng/mL

 
Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             
Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile 10 mM acetic acid at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date                     
12 months from date of receipt when stored at -20°C to -80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

To receive more information or for a bulk quote, email us at quotes@shenandoah-bt.com.

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 0718 Lot 0718
SDS Lot 0409  
PDS Animal-Free Lot 0718 Animal-Free  
SDS Animal-Free    

 

Papers that use this product:
 
 
 
 2017 May 31;37(12). pii: e00437-16. doi: 10.1128/MCB.00437-16. Print 2017 Jun 15. PMID 28373291

Dual Mechanism of Rag Gene Repression by c-Myb during Pre-B Cell Proliferation.


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