Mouse IL-22

Interleukin 22 (IL-22), also called IL-TIF, is an IL-10 family member that is produced by activated dendritic cells and T lymphocytes.  IL-22 signals via a heteroduplex receptor consisting of IL-22R and IL-10RB chains.  IL-22 is a potent mediator of cellular inflammatory responses and wound healing.  

SKU Select size Price Buy
200-77-2ug Mini: 2 ug $63.00 + -
200-77-10ug Std.: 10 ug $158.00 + -
200-77-100ug Value: 100 ug $609.00 + -
200-77-500ug Midgi: 500 ug $3,024.00 + -
200-77-1mg Mg: 1 mg $5,040.00 + -
200-77AF-2ug Animal-Free Mini: 2 ug $69.00 + -
200-77AF-10ug Animal-Free Std.: 10 ug $174.00 + -
200-77AF-100ug Animal-Free Value: 100 ug $667.00 + -
200-77AF-500ug Animal-Free Midgi: 500 ug $3,329.00 + -
200-77AF-1mg Animal-Free Mg: 1 mg $5,544.00 + -

Alternate Names:  IL-TIF        Accession Number: Q9JJY9
Description:  Interleukin 22 (IL-22), also called IL-TIF, is an IL-10 family member that is produced by activated dendritic cells and T lymphocytes.  IL-22 signals via a heteroduplex receptor consisting of IL-22R and IL-10RB chains.  IL-22 is a potent mediator of cellular inflammatory responses and wound healing.  
Source:  Genetically modified E.coli.
Predicted MW: Monomer, 16.8 kDa (147 aa)
AA Sequence:   MLPVNTRCKL EVSNFQQPYI VNRTFMLAKE ASLADNNTDV RLIGEKLFRG VSAKDQCYLM KQVLNFTLED VLLPQSDRFQ PYMQEVVPFL TKLSNQLSSC HISGDDQNIQ KNVRRLKETV KKLGESGEIK AIGELDLLFM SLRNACV
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

Production of IL-10 from human COLO-205 cells

≤1 ng/mL

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date                      
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

To receive more information or for a bulk quote, email us at quotes@shenandoah-bt.com.

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 0315 Lot 0315
SDS Lot 0315 Animal-Free  
PDS Animal-Free    
SDS Animal-Free    

 

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