Mouse / Rat RANTES (CCL5)

Regulated upon activation, normal T cell expressed and secreted (RANTES), also called CCL5, is a chemokine produced by T cells three to five days after T cell activation. RANTES signals through G protein-coupled receptors CCR5, CCR3, CCR1, and through the human CMV-encoded viral receptor US28.

SKU Select size Price Buy
800-08-5ug Mini: 5 ug $63.00 + -
800-08-20ug Std.: 20 ug $158.00 + -
800-08-100ug Value: 100 ug $394.00 + -
800-08-500ug Midgi: 500 ug $1,701.00 + -
800-08-1mg Mg: 1 $2,835.00 + -

Catalog Number: 800-08 is a replacement number for mouse 200-45 / rat 300-26 (100% sequence identity)

Alternate Names:  CCL5               Accession Number: Q5XZF2
Description:  Regulated upon activation, normal T cell expressed and secreted (RANTES), also called CCL5, is a chemokine produced by T cells three to five days after T cell activation. RANTES signals through G protein-coupled receptors CCR5, CCR3, CCR1, and through the human CMV-encoded viral receptor US28. RANTES functions to recruit immune cells to inflammatory sites.
Source:  Genetically modified E.coli.
Predicted MW: Monomer, 7.9 kDa (68 aa)
AA Sequence:  SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

THP-1 chemotaxis

≤250 ng/mL 

Preparation and Storage

Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date:                      
12 months from date of receipt when stored at -20°C to -80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

To receive more information or for a bulk quote, email us at quotes@shenandoah-bt.com.

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 1108 Lot 0515
SDS Lot 0515 Lot 0113

 

Papers that use this product:
 
 
 
 2015 Sep;1850(9):1862-8. doi: 10.1016/j.bbagen.2015.05.008. Epub 2015 May 15. PMID 25986989

Single-cell analysis of mast cell degranulation induced by airway smooth muscle-secreted chemokines.


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