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Human IL-32 alpha

Interleukin 32 alpha (IL-32 α) is one of six known splice variants of the IL-32 gene. IL-32 α induces the macrophage production of inflammatory cytokines, such as interleukin 8 (IL-8), tumor necrosis factor-alpha (TNF-α), and macrophage inflammatory protein 2 (MIP-2). IL-32 α expression is increased after the activation of T cells, natural killer (NK) cells, and interferon gamma-treated epithelial cells.

SKU Select size Price Buy
100-151-2ug Mini: 2 ug $65.00 + -
100-151-10ug Std.: 10 ug $163.00 + -
100-151-100ug Value: 100 ug $62.00 + -
100-151-500ug Midgi: 500 ug $3,115.00 + -
100-151-1mg Mg: 1 mg $5,191.00 + -

Alternate Names:  NK4               Accession Number: P24001-4
Description:  Interleukin 32 alpha (IL-32 α) is one of six known splice variants of the IL-32 gene. IL-32 α induces the macrophage production of inflammatory cytokines, such as interleukin 8 (IL-8), tumor necrosis factor-alpha (TNF-α), and macrophage inflammatory protein 2 (MIP-2). IL-32 α expression is increased after the activation of T cells, natural killer (NK) cells, and interferon gamma-treated epithelial cells.
Source:  Genetically modified E.coli.
Predicted MW: Monomer, 14.9 kDa (131 aa)
AA Sequence:  MCFPKVLSDD MKKLKARMHQ AIERFYDKMQ NAESGRGQVM SSLAELEDDF KEGYLETVAA YYEEQHPELT PLLEKERDGL RCRGNRSPVP DVEDPATEEP GESFCDKSYG APRGDKEELT PQKCSEPQSS K
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 50 mM sodium phosphate, pH 7.5

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

No biological activity data is available at this time

No biological activity data is available at this time 

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date:                      
12 months from date of receipt when stored at -20°C to -80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

  

 

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Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 0908 Lot 0908
SDS    
Papers that use this product:
 
 
 2016 Mar;113(4):364-9. doi: 10.1002/jso.24142. Epub 2016 Jan 12. PMID 27100023

IL-32α has differential effects on proliferation and apoptosis of human melanoma cell lines.

Nicholl MB1,2Chen X1,3Qin C1,3Bai Q1Zhu Z1Davis MR1Fang Y1,4.

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