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Human GDF-15

Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor beta (TGF-β) family and is made by the placenta and cardiovascular tissues. GDF-15 regulates inflammatory and apoptotic pathways during cellular stress and injury.

SKU Select size Price Buy
100-171-5ug Mini: 5 ug $65.00 + -
100-171-20ug Std.: 20 ug $163.00 + -
100-171-100ug Value: 100 ug $459.00 + -
100-171-500ug Midgi: 500 ug $2,271.00 + -
100-171-1mg Mg: 1 mg $3,785.00 + -
100-171AF-5ug Animal-Free Mini: 5 ug $70.00 + -
100-171AF-20ug Animal-Free Std.: 20 ug $178.00 + -
100-171AF-100ug Animal-Free Value: 100 ug $503.00 + -
100-171AF-500ug Animal-Free Midgi: 500 ug $2,499.00 + -
100-171Af-1mg Animal-Free Mg: 1 mg $4,164.00 + -

Alternate Names:  MIC-1, Placental TGF-β, Prostate differentiation factor              

Accession Number: Q99988
Description:  Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor beta (TGF-β) family and is made by the placenta and cardiovascular tissues. GDF-15 regulates inflammatory and apoptotic pathways during cellular stress and injury. GDF-15 is emerging as a biomarker of early heart disease, such that increased levels of circulating GDF-15 are associated with an increased risk of developing heart failure.
Source:  Genetically modified E.coli.
Predicted MW: Dimer, 12.4/24.8 kDa (113/226 aa)
AA Sequence:  MARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLIQKTDTGVSLQ TYDDLLAKDC HCI
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

No biological activity data is available at this time

No biological activity data is available at this time 

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date:                      
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

To receive more information or a bulk quote, email us at quotes@shenandoah-bt.com.

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 1115 Lot 1115
SDS Lot 0618  
PDS Animal-Free Lot 1115 Animal-Free  
SDS Animal-Free    

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