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Human FGF-6

Fibroblast growth factor 6 (FGF-6) is a heparin-binding growth factor that is expressed in epithelial and mesenchymal lineages. FGF-6 binds and signals through the FGF receptors FGFR1, FGFR2, and FGFR4. FGF-6 functions as a mitogen for vascular endothelial cells and fibroblasts. FGF-6 is also an important factor driving muscle differentiation and regeneration.

SKU Select size Price Buy
100-201-5ug Mini: 5 ug $67.00 + -
100-201-25ug Std.: 25 ug $168.00 + -
100-201-100ug Value: 100 ug $502.00 + -
100-201-500ug Midgi: 500 ug $2,006.00 + -
100-201-1mg Mg: 1 mg $3,008.00 + -
100-201AF-5ug Animal-Free Mini: 5 ug $73.00 + -
100-201AF-25ug Animal-Free Std.: 25 ug $184.00 + -
100-201AF-100ug Animal-Free Value: 100 ug $553.00 + -
100-201AF-500ug Animal-Free Midgi: 500 ug $2,206.00 + -
100-201AF-1mg Animal-Free Mg: 1 mg $3,310.00 + -

Alternate Names:  Heparin secretory-transforming protein 2, HST-2, HSTF-2, Heparin-binding growth factor 6, HBGF-6               Accession Number: P10767 

Description:  Fibroblast growth factor 6 (FGF-6) is a heparin-binding growth factor that is expressed in epithelial and mesenchymal lineages. FGF-6 binds and signals through the FGF receptors FGFR1, FGFR2, and FGFR4. FGF-6 functions as a mitogen for vascular endothelial cells and fibroblasts. FGF-6 is also an important factor driving muscle differentiation and regeneration.
Source:  Genetically modified E.coli.
Predicted MW: Monomer, 18.9 kDa (169 aa)
AA Sequence:  MGTRANNTLL DSRGWGTLLS RSRAGLAGEI AGVNWESGYL VGIKRQRRLY CNVGIGFHLQ VLPDGRISGT HEENPYSLLE ISTVERGVVS LFGVRSALFV AMNSKGRLYA TPSFQEECKF RETLLPNNYN AYESDLYQGT YIALSKYGRV KRGSKVSPIM TVTHFLPRI
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate and 50 mM sodium chloride, pH 7.5

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

3T3 Proliferation w 1 ug heparin

≤1 ng/mL; ≥ 1.0 x 10^6 units/mg

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. If a precipitate is observed, centrifuge the solution thoroughly and use only the soluble fraction (removing it from the precipitate). A 10% overfill has been added to compensate for any loss of protein in the precipitate. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date:                      
12 months from date of receipt when stored at -20°C to -80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

To receive more information or a bulk quote, email us at quotes@shenandoah-bt.com.

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 0716 Lot 0218
SDS Lot 0218 Lot 0716
PDS Animal-Free Lot 0716 Animal-Free  
SDS Animal-Free Lot 0218 Animal-Free  

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