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Human beta-NGF

Nerve growth factor beta (beta-NGF) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. beta-NGF signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways.

SKU Select size Price Buy
100-38-5ug Mini: 5 ug $67.00 + -
100-38-20ug Std.: 20 ug $168.00 + -
100-38-100ug Value: 100 ug $419.00 + -
100-38-500ug Midgi: 500 ug $1,805.00 + -
100-38-1mg Mg: 1 mg $3,008.00 + -
100-38AF-5ug Animal-Free Mini: 5 ug $73.00 + -
100-38AF-20ug Animal-Free Std.: 20 ug $184.00 + -
100-38AF-100ug Animal-Free Value: 100 ug $463.00 + -
100-38AF-500ug Animal-Free Midgi: 500 ug $1,983.00 + -
100-38AF-1mg Animal-Free Mg: 1 mg $3,310.00 + -

Alternate Names:  β-NGF               Accession Number: P01138
Description:  Nerve growth factor beta (beta-NGF) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. beta-NGF signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. beta-NGF is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat beta-NGF proteins are cross-reactive.
Source:  Genetically modified E.coli.
Predicted MW: Dimer, 13.6/27.3 kDa (121/242 aa)
AA Sequence:  MSSSHPIFHR GEFSVCDSVS VWVGDKTTAT DIKGKEVMVL GEVNINNSVF KQYFFETKCR DPNPVDSGCR GIDSKHWNSY CTTTHTFVKA LTMDGKQAAW RFIRIDTACV CVLSRKAVRR A
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

TF-1 cell proliferation

≤5 ng/mL

 
Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             
Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date                      
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

To receive more information or for a bulk quote, email us at quotes@shenandoah-bt.com.

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 1116 Lot 0513
SDS Lot 0708 Lot 1116
PDS Animal-Free Lot 0611  
SDS Animal-Free Lot 0513  
  Lot 1116 Animal-Free  
  Lot 0513 Animal-Free  

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