Mouse IL-15 Gel
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Mouse IL-15

Limited Inventory!  

This product will be discontinued when inventory is depleted.

SKU Select size Price Buy
200-07-2ug Mini: 2 ug $60.00 + -
200-07-10ug Std.: 10 ug $150.00 + -
200-07-100ug Value: 100 ug $435.00 + -
200-07-500ug Midgi: 500 ug $2160.00 + -
200-07-1mg Mg: 1 mg $3600.00 + -
200-07AF-2ug Animal-Free Mini: 2 ug $65.00 + -
200-07AF-10ug Animal-Free Std.: 10 ug $165.00 + -
200-07AF-100ug Animal-Free Value: 100 ug $475.00 + -
200-07AF-500ug Animal-Free Midgi: 500 ug $2375.00 + -
200-07AF-1mg Animal-Free Mg: 1 mg $3960.00 + -
  • Weight
    0.0100 lbs
  • SKU
    200-07-2ug

Alternate Names:  IL-T               Accession Number: P48346
Description:  Interleukin 15 (IL-15) is a widely expressed proinflammatory cytokine that is structurally and functionally related to interleukin 2 (IL-2). IL-15 signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors. IL-15 regulates the activation of T cells, neutrophils, and macrophages, and is a stimulatory cytokine promoting dendritic cell function. IL-15 expression is dysregulated in chronic inflammatory disorders, including rheumatoid arthritis, psoriasis, and pulmonary inflammatory diseases. Therefore, IL-15 may serve as an effective therapeutic target, due to the beneficial outcomes of IL-15 neutralization in models of psoriasis and diabetes.
Source:  Genetically modified E.coli.
Predicted MW: Monomer, 13.4 kDa (115 aa)
AA Sequence:  MNWIDVRYDL EKIESLIQSI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VAESGCKECE ELEEKTFTEF LQSFIRIVQM FINTS
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

CTLL-2 cell proliferation

≤20 ng/mL; ≥ 5.0 x 10^4 units/mg

(typical ED50 is < 10 ng/mL)

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date                      
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

 

 

To receive more information or a quote, complete our bulk/custom order form.

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 0816 Lot 0816
SDS Lot 0212  
PDS Animal-Free Lot 1214  
SDS Animal-Free  Lot 0816 Animal-Free  
  Lot 1214 Animal-Free  
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