Mouse IL-10 Gel
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Mouse IL-10

Animal-Free (AF) proteins are identical to regular proteins and include additional documentation showing that they were produced with no materials of animal or human origin using ANIMAL-FREE purification processes.  Learn more HERE.

SKU Select size Price Buy
200-84-2ug Mini: 2 ug $63.00 + -
200-84-10ug Std.: 10 ug $158.00 + -
200-84-100ug Value: 100 ug $725.00 + -
200-84-500ug Midgi: 500 ug $3024.00 + -
200-84-1mg Mg: 1 mg $5040.00 + -
200-84AF-2ug Animal-Free Mini: 2 ug $69.00 + -
200-84AF-10ug Animal-Free Std.: 10 ug $174.00 + -
200-84AF-100ug Animal-Free Value: 100 ug $798.00 + -
200-84AF-500ug Animal-Free Midgi: 500 ug $3329.00 + -
200-84AF-1mg Animal-Free Mg: 1 mg $5544.00 + -
  • Weight
    0.0100 lbs
  • SKU
    200-84-2ug

Alternate Names:  Cytokine synthesis inhibitory factor, CSIF           

Accession Number: P18893
Description:  Interleukin 10 (IL-10) is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells. IL-10 inhibits the production of pro-inflammatory cytokines such as interferon gamma (IFNƴ), tumor necrosis factor alpha (TNFα), interleukin 2 (IL-2), interleukin 3 (IL-3), interleukin 4 (IL-4), and granulocyte-macrophage colony-stimulating factor (GM-CSF), made by macrophages and regulatory T cells. IL-10 also suppresses antigen presentation on antigen presenting cells, and enhances the survival, proliferation, and antibody production of B cells. Mouse IL-10 is not active on human cells.
Source:  Genetically modified E.coli.
Predicted MW: Noncovalent homodimer, 18.9 kDa (161 aa)
AA Sequence:  MSRGQYSRED NNCTHFPVGQ SHMLLELRTA FSQVKTFFQT KDQLDNILLT DSLMQDFKGY LGCQALSEMI QFYLVEVMPQ AEKHGPEIKE HLNSLGEKLK TLRMRLRRCH RFLPCENKSK AVEQVKSDFN KLQDQGVYKA MNEFDIFINC IEAYMMIKMK S
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

MC/9 cell proliferation

≤5 ng/mL; ≥ 2.0 x 10^5 units/mg

 

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date                      
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

 To receive more information or a quote, complete our bulk/custom order form.

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 0316 Lot 07193
SDS Lot 0316 Animal-Free Lot 04182
PDS Animal-Free Lot 04181 Lot 04181
SDS Animal-Free   Lot 0316
    Lot 0219
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