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Mouse IFN-gamma Bioassay
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Mouse IFN-gamma

Animal-Free (AF) proteins are identical to regular proteins and include additional documentation that they were produced using ANIMAL-FREE PROCESSES and contain only ANIMAL-FREE RAW MATERIALS.  Learn more HERE.

SKU Select size Price Buy
200-16-20ug Mini: 20 ug $63.00 + -
200-16-100ug Std.: 100 ug $158.00 + -
200-16-250ug Value: 250 ug $363.00 + -
200-16-500ug Midgi: 500 ug $604.00 + -
200-16-1mg Mg: 1 mg $1050.00 + -
200-16AF-20ug Animal-Free Mini: 20 ug $69.00 + -
200-16AF-100ug Animal-Free Std.: 100 ug $174.00 + -
200-16AF-250ug Animal-Free Value: 250 ug $399.00 + -
200-16AF-500ug Animal-Free Midgi: 500 ug $662.00 + -
200-16AF-1mg Animal-Free Mg: 1 mg $1155.00 + -
  • Weight
    0.0100 lbs
  • SKU
    200-16-20ug

Alternate Names:  Type II interferon, T cell interferon, Immune Interferon, MAF               Accession Number: P01580
Description:  Interferon gamma (IFN-γ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN-γ is produced by T cells and natural killer cells following antigen-specific activation. IFN-γ binds IFN-γ receptors (IFN-γ R1 and IFN-γ R2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFN-γ-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules. Mouse IFN-γ is not cross-reactive with human IFN-γ.
Source:  Genetically modified E.coli.
Predicted MW: Monomer, 15.7 kDa (134 aa)
AA Sequence:  MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

Viral CPE assay using EMC virus on L929 cells

≥ 1.0 x 10^7 units/mg

 

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. If a precipitate is observed, centrifuge the solution thoroughly and use only the soluble fraction (removing it from the precipitate). A 10% overfill has been added to compensate for any loss of protein in the precipitate. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.  

Expiration Date:                      
12 months from date of receipt when stored at -20°C to -80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

To receive more information or a quote, complete our bulk/custom order form.

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 1107 Lot 0416
SDS Lot 0416 Lot 1107
PDS Animal-Free Lot 0416 Animal-Free  
SDS Animal-Free    

 

Papers that use this product:
 
 
 
 

 2015 Aug;3(8):946-55. doi: 10.1158/2326-6066.CIR-14-0206. Epub 2015 Jun 3.

PD-1 or PD-L1 Blockade Restores Antitumor Efficacy Following SSX2 Epitope-Modified DNA Vaccine Immunization.


SAMe prevents the induction of the immunoproteasome and preserves the 26S proteasome in the DDC-induced MDB mouse model.


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