Mouse GM-CSF

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is hematopoietic growth factor produced by endothelial cells, monocytes, fibroblasts, and T cells. GM-CSF stimulates the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells. GM-CSF promotes immune system development and regulates neutrophil function during infection. Human and mouse GM-CSF show no cross-reactivity.

SKU Select size Price Buy
200-15-5ug Mini: 5 ug $63.00 + -
200-15-20ug Std.: 20 ug $158.00 + -
200-15-100ug Value: 100 ug $394.00 + -
200-15-500ug Midgi: 500 ug $1,764.00 + -
200-15-1mg Mg: 1 mg $2,940.00 + -
200-15AF-5ug Animal-Free Mini: 5 ug $69.00 + -
200-15AF-20ug Animal-Free Std.: 20 ug $174.00 + -
200-15AF-100ug Animal-Free Value: 100 ug $436.00 + -
200-15AF-500ug Animal-Free Midgi: 500 ug $1,943.00 + -
200-15AF-1mg Animal-Free Mg: 1 mg $3,234.00 + -

Alternate Names:  CSF-2, Pluripoietin-α, MGI-1GM               Accession Number: P01587
Description:  Granulocyte-macrophage colony-stimulating factor (GM-CSF) is hematopoietic growth factor produced by endothelial cells, monocytes, fibroblasts, and T cells. GM-CSF stimulates the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells. GM-CSF promotes immune system development and regulates neutrophil function during infection. Human and mouse GM-CSF show no cross-reactivity.
Source:  Genetically modified E.coli.
Predicted MW: Monomer, 14.3 kDa (125 aa)
AA Sequence:  MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM acetic acid

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

FDCP-1 cell proliferation

≤50 pg/mL

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.
 
Expiration Date                      
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.
 

To receive more information or for a bulk quote, email us at quotes@shenandoah-bt.com.

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 0108 Lot 0114
SDS Lot 0108 Lot 0818
PDS Animal-Free Lot 0818 Animal-Free  
SDS Animal-Free    
Papers that cite this product:
 
 

 2019 Jan 15;10(2):36. doi: 10.1038/s41419-018-1285-3. PMID 30674867

Nanoparticle enhanced MRI can monitor macrophage response to CD47 mAb immunotherapy in osteosarcoma.


 2019 Apr;176(7):938-949. doi: 10.1111/bph.14597. Epub 2019 Mar 14. PMID 30706444

Blockage of sphingosine-1-phosphate receptor 2 attenuates allergic asthma in mice.


  2018 Jun 21;3(12). pii: 91894. doi: 10.1172/jci.insight.91894. eCollection 2018 Jun 21. PMID 29925696
 2018 Sep 15;10(9):2859-2867. eCollection 2018.  PMID 30323872

Mouse dendritic cell migration in abdominal lymph nodes by intraperitoneal administration.

Wang B1,2Sun C2,3Wang S4,5Shang N2Shangguan J2Figini M2Pan L2,6Zhou K2Ma Q2Procissi D2Velichko Y2,7Yaghmai V2,7Li G1Zhang Z2,7.

Nat Nanotechnol 2018 Dec;13(12):1174-1181.  doi: 10.1038/s41565-018-0271-3. PMID 30297818

A Malaria Vaccine Adjuvant Based on Recombinant Antigen Binding to Liposomes

 2017 Mar;101(3):693-702. doi: 10.1189/jlb.3AB0416-189RR. Epub 2016 Oct 12. PMID 27733578

Rab27a regulates GM-CSF-dependent priming of neutrophil exocytosis.


 2013 May;123(5):2287-97. doi: 10.1172/JCI63802. Epub 2013 Apr 15. PMID 23585480

IL-33-dependent induction of allergic lung inflammation by FcγRIII signaling.


 

 2013 Dec 4;8(12):e81269. doi: 10.1371/journal.pone.0081269. eCollection 2013. PMID 24324683

Lack of RNase L attenuates macrophage functions.