Human VEGF-121

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with one being VEGF-121. The VEGF-121 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell function.

SKU Select size Price Buy
100-116-2ug Mini: 2 ug $63.00 + -
100-116-10ug Std.: 10 ug $158.00 + -
100-116-100ug Value: 100 ug $457.00 + -
100-116-500ug Midgi: 500 ug $2,268.00 + -
100-116-1mg Mg: 1 mg $3,780.00 + -
100-116AF-2ug Animal-Free Mini: 2 ug $69.00 + -
100-116AF-10ug Animal-Free Std.: 10 ug $174.00 + -
100-116AF-100ug Animal-Free Value: 100 ug $499.00 + -
100-116AF-500ug Animal-Free Midgi: 500 ug $2,494.00 + -
100-116AF-1mg Animal-Free Mg: 1 mg $4,158.00 + -

Alternate Names:  VEGF-A, VPF, glioma-derived endothelial cell mitogen              

Accession Number: P15692-9
Description:  Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with one being VEGF-121. The VEGF-121 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell function.
Source:  Genetically modified E.coli.
Predicted MW: Dimer, 14.1/28.3 kDa (121/242 aa)
AA Sequence:  MPMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENCDKPR R
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

HUVEC proliferation

≤5 ng/mL; ≥ 2.0 x 10^5 units/mg

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date:                      
12 months from date of receipt when stored at -20°C to -80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

 

Complementary antibody products:
Need an Anti-Human VEGF-121 antibody?  We recommend Anti-Human VEGF-121 Rabbit Polyclonal Antibody from ImmunoReagents.  If you are curious to know more about the relationship between Shenandoah and Immunoreagents, click here for the scoop.

To receive more information or for a bulk quote, email quotes@shenandoah-bt.com.

  

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 1112 Lot 0713
SDS Lot 1007  
PDS Animal-Free Lot 0713  
SDS Animal-Free Lot 0713 Animal-Free  

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