Human RELM-beta

Resistin-like molecule-beta (RELM-β) is a member of the RELM family of secreted proteins containing conserved C-terminus cysteines. The RELM family consists of Resistin (FIZZ3), RELM-α (FIZZ1), RELM-β (FIZZ2), and RELM-ɣ (FIZZ4). Resistin and RELM-β are the only RELM family members found in humans, whereas all four RELM family members are present in rodents. RELM-β functions to increase fibroblast proliferation and differentiation, resulting in airway remodelling and increased inflammation.

SKU Select size Price Buy
100-160-5ug Mini: 5 ug $63.00 + -
100-160-25ug Std.: 25 ug $158.00 + -
100-160-100ug Value: 100 ug $394.00 + -
100-160-500ug Midgi: 500 ug $1,701.00 + -
100-160-1mg Mg: 1 mg $2,835.00 + -
100-160AF-5ug Animal-Free Mini: 5 ug $69.00 + -
100-160AF-25ug Animal-Free Std.: 25 ug $174.00 + -
100-160AF-100ug Animal-Free Value: 100 ug $436.00 + -
100-160AF-500ug Animal-Free Midgi: 500 ug $1,869.00 + -
100-160AF-1mg Animal-Free Mg: 1 mg $3,119.00 + -

Alternate Names:  FIZZ2               Accession Number: Q2UXL7
Description:  Resistin-like molecule-beta (RELM-β) is a member of the RELM family of secreted proteins containing conserved C-terminus cysteines. The RELM family consists of Resistin (FIZZ3), RELM-α (FIZZ1), RELM-β (FIZZ2), and RELM-ɣ (FIZZ4). Resistin and RELM-β are the only RELM family members found in humans, whereas all four RELM family members are present in rodents. RELM-β functions to increase fibroblast proliferation and differentiation, resulting in airway remodelling and increased inflammation.
Source:  Genetically modified E.coli.
Predicted MW: Noncovalent Homodimer, 9.5/19.0 kDa (89/178 aa)
AA Sequence:  MQCSLDSVMD KKIKDVLNSL EYSPSPISKK LSCASVKSQG RPSSCPAGMA VTGCACGYGC GSWDVQLETT CHCQCSVVDW TTARCCHLT
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥90%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

No biological activity data is available at this time

No biological activity data is available at this time 

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date:                      
12 months from date of receipt when stored at -20°C to -80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

  

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Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 0409 Lot 0215
SDS Lot 0617 Lot 0617
PDS Animal-Free Lot 1209 Animal-Free  
SDS Animal-Free Lot 0617 Animal-Free  

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