Human Persephin

 Persephin is a neurotrophic factor of the glial cell line-derived neurotrophic factor (GDNF) family. Persephin promotes survival and growth of dopaminergic and motor neurons, but not peripheral neurons. Persephin is a ligand for the RET receptor tyrosine kinase.

SKU Select size Price Buy
100-81-5UG Mini: 5 ug $63.00 + -
100-81-20UG Std.: 20 ug $158.00 + -
100-81-100UG Value: 100 ug $394.00 + -
100-81-500UG Midgi: 500 ug $1,701.00 + -
100-81-1MG Mg: 1 mg $2,835.00 + -
100-81AF-5UG Animal-Free Mini: 5 ug $69.00 + -
100-81AF-20UG Animal-Free Std.: 20 ug $174.00 + -
100-81AF-100UG Animal-Free Value: 100 ug $436.00 + -
100-81AF-500UG Animal-Free Midgi: 500 ug $1,869.00 + -
100-81AF-1MG Animal-Free Mg: 1 mg $3,119.00 + -
Alternate Names:  PSP               Accession Number: O60542
Description:  Persephin is a neurotrophic factor of the glial cell line-derived neurotrophic factor (GDNF) family. Persephin promotes survival and growth of dopaminergic and motor neurons, but not peripheral neurons. Persephin is a ligand for the RET receptor tyrosine kinase.
Source:  Genetically modified E.coli.
Predicted MW: Dimer, 10.4/20.8 kDa (97/194 aa)
AA Sequence:  MALSGPCQLW SLTLSVAELG LGYASEEKVI FRYCAGSCPR GARTQHGLAL ARLQGQGRAH GGPCCRPTRY TDVAFLDDRH RWQRLPQLSA AACGCGG
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

TT cell proliferation

≤20 ng/mL 

 
Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             
Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date                      
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

To receive more information or for a bulk quote, email us at quotes@shenandoah-bt.com.

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 1014 Lot 1014
SDS Lot 1014 Animal-Free  
PDS Animal-Free    
SDS Animal-Free    

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