Human / Mouse TGF-beta 3 (Liquid)

Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-β family of proteins signal through serine/threonine kinase receptors. TGF-β isoforms (TGF-β1, -β2, and –β3) have overlapping, yet distinct biological actions in developing and adult tissues.

SKU Select size Price Buy
800-07-2ug Mini: 2 ug $63.00 + -
800-07-10ug Std.: 10 ug $158.00 + -
800-07-100ug Value: 100 ug $615.00 + -
800-07-500ug Midgi: 500 ug $3,024.00 + -
800-07-1mg Mg: 1 mg $5,040.00 + -
800-07AF-2ug Animal-Free Mini: 2 ug $69.00 + -
800-07AF-10ug Animal-Free Std.: 10 ug $174.00 + -
800-07AF-100ug Animal-Free Value: 100 ug $678.00 + -
800-07AF-500ug Animal-Free Midgi: 500 ug $3,329.00 + -
800-07AF-1mg Animal-Free Mg: 1 mg $5,544.00 + -

Catalog Number: 800-07 is a replacement for human 100-109 / mouse 200-27 (100% sequence identity)

Accession Number: P10600
Description:  Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-β family of proteins signal through serine/threonine kinase receptors. TGF-β isoforms (TGF-β1, -β2, and –β3) have overlapping, yet distinct biological actions in developing and adult tissues. TGF-β3 is an important factor in regulating cell adhesion and accelerating wound repair. TGF-β3 also functions during osteoblast proliferation, chemotaxis, and collagen synthesis.
Source:  Genetically modified E.coli.
Predicted MW: Dimer, 12.9/25.7 kDa (113/226 aa)
AA Sequence:  MALDTNYCFR NLEENCCVRP LYIDFRQDLG WKWVHEPKGY YANFCSGPCP YLRSADTTHS TVLGLYNTLN PEASASPCCV PQDLEPLTIL YYVGRTPKVE QLSNMVVKSC KCS
Formulation:  In solution: 10 mM acetic acid and 20% Ethanol at a concentration of 0.25 mg/mL

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

Inhibition of IL-4-induced HT-2 cell proliferation

≤1 ng/mL 

Preparation and Storage

Country of Origin:  USA        Shipping:  Ice pack             
Storage:  Centrifuge vial before opening. DO NOT VORTEX. Store at 4°C.

Expiration Date:                      
12 months from date of receipt when stored at 4°C as supplied.

To receive more information or for a bulk quote, email us at quotes@shenandoah-bt.com.

  

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 0712 Lot 0213
SDS  Lot 0317 Lot 0317
PDS Animal-Free  Lot 0213   
SDS Animal-Free  Lot 0317 Animal-Free   
  Lot 0213 Animal-Free  

 

Papers that use this product:
 
 
 2017 Jun;66(6):737-751. doi: 10.1007/s00262-017-1965-3. Epub 2017 Mar 9. PMID 28280853

Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis.


 2014 Oct 1;549(1):134-40. doi: 10.1016/j.gene.2014.07.056. Epub 2014 Jul 23. PMID 25062971

A role for IL-10 in the transcriptional regulation of Roquin-1.



Related products