Human IL-5

Interleukin 5 (IL-5) is a hematopoietic growth factor that is expressed in type 2 T helper (Th2) cells, mast cells, and eosinophils. IL-5 acts through the IL-5 receptor (IL-5R), stimulates B cell growth, and mediates eosinophil activation. Human and mouse IL-5 show cross-reactivity.

SKU Select size Price Buy
100-191-2ug Mini: 2 ug $63.00 + -
100-191-10ug Std.: 10 ug $158.00 + -
100-191-100ug Value: 100 ug $510.00 + -
100-191-500ug Midgi: 500 ug $2,520.00 + -
100-191-1mg Mg: 1 mg $4,200.00 + -
100-191AF-2ug Animal-Free Mini: 2 ug $69.00 + -
100-191AF-10ug Animal-Free Std.: 10 ug $174.00 + -
100-191AF-100ug Animal-Free Value: 100 ug $562.00 + -
100-191AF-500ug Animal-Free Midgi: 500 ug $2,772.00 + -
100-191AF-1mg Animal-Free Mg: 1 mg $4,620.00 + -

Alternate Names:  B-cell differentiation factor I, Eosinophil differentiation factor, TRF               Accession Number: P05113
Description:  Interleukin 5 (IL-5) is a hematopoietic growth factor that is expressed in type 2 T helper (Th2) cells, mast cells, and eosinophils. IL-5 acts through the IL-5 receptor (IL-5R), stimulates B cell growth, and mediates eosinophil activation. Human and mouse IL-5 show cross-reactivity.
Source:  Genetically modified E.coli.
Predicted MW: Dimer, 13.3/26.6 kDa (116/232 aa)
AA Sequence:  MIPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium glycinate, pH 8.5

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

TF-1 cell proliferation

≤250 pg/mL; ≥ 4.0 x 10^6 units/mg

 
Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             
Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date:                      
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

To receive more information or a bulk quote, email us at quotes@shenandoah-bt.com.

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 0615 Lot 0615
SDS Lot 0615 Animal-Free  
PDS Animal-Free    
SDS Animal-Free    

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