Human GDF-15-D Gel
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Human GDF-15-D

MIC-1, Placental TGFβ, Prostate differentiation factor

SKU Select size Price Buy
100-172-5ug Mini: 5 ug $63.00 + -
100-172-20ug Std.: 20 ug $158.00 + -
100-172-100ug Value: 100 ug $447.00 + -
100-172-500ug Midgi: 500 ug $2205.00 + -
100-172-1mg Mg: 1 $3675.00 + -
  • Weight
    0.0100 lbs
  • SKU
    100-172-5ug

Alternate Names:  MIC-1, Placental TGF-β, Prostate differentiation factor              

Accession Number: Q99988
Description:  Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor beta (TGF-β) family and is made by the placenta and cardiovascular tissues. GDF-15 regulates inflammatory and apoptotic pathways during cellular stress and injury. GDF-15 is emerging as a biomarker of early heart disease, such that increased levels of circulating GDF-15 are associated with an increased risk of developing heart failure. The GDF-15 D variant has a Histidine to an Aspartate substitution at amino acid position 7.
Source:  Genetically modified E.coli.
Predicted MW: Dimer, 12.4/24.8 kDa (113/226 aa)
AA Sequence:  MARNGDDCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLI QKTDTGVSLQ TYDDLLAKDC HCI
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

No biological activity data is available at this time

No biological activity data is available at this time

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date:                      
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

 

To receive more information or a quote, complete our bulk/custom order form.

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 0610 Lot 1115
SDS   Lot 0610 D Mutant
    Lot 1115 Animal-Free
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