Human FGF-7 Gel
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Human FGF-7

Animal-Free (AF) proteins are identical to regular proteins and include additional documentation that they were produced using ANIMAL-FREE PROCESSES and contain only ANIMAL-FREE RAW MATERIALS.  Learn more HERE.

SKU Select size Price Buy
100-187-2ug Mini: 2 ug $63.00 + -
100-187-10ug Std.: 10 ug $158.00 + -
100-187-100ug Value: 100 ug $609.00 + -
100-187-500ug Midgi: 500 ug $3024.00 + -
100-187-1mg Mg: 1 mg $5040.00 + -
100-187AF-2ug Animal-Free Mini: 2 ug $69.00 + -
100-187AF-10ug Animal-Free Std.: 10 ug $174.00 + -
100-187AF-100ug Animal-Free Value: 100 ug $667.00 + -
100-187AF-500ug Animal-Free Midgi: 500 ug $3329.00 + -
100-187AF-1mg Animal-Free Mg: 1 mg $5544.00 + -
  • Weight
    0.0100 lbs
  • SKU
    100-187-2ug

Alternate Names:  KGF               Accession Number: P21781
Description:  Fibroblast growth factor 7 (FGF-7), also known as keratinocyte growth factor (KGF), is a potent mitogen that regulates epithelial cell migration and differentiation.  FGF-7 is produced by mesenchymal cells and binds in high affinity to a splice variant of FGF receptor 2 (FGFR2-IIIb).  The mitogenic activity of FGF-7 acts predominantly on keratinocytes, but not on fibroblast or endothelial cells.  FGF-7 expression is upregulated after acute and chronic injury, suggesting that FGF-7 functions during the healing of injured epithelial cells.  FGF-7 also induces the formation of the apical ectodermal ridge during limb development.
Source:  Genetically modified E.coli.
Predicted MW: Monomer, 19 kDa (164 aa)
AA Sequence:  MCNDMTPEQM ATNVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVALNQK GIPVRGKKTK KEQKTAHFLP MAIT
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 100 mM sodium chloride, pH 7.5

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥90%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

4MBr-5 cell proliferation

≤60 ng/mL; ≥ 1.7 x 10^4 units/mg

(typical ED50 is < 5 ng/mL)

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date:                      
12 months from date of receipt when stored at -20°C to -80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

To receive more information or a quote, complete our bulk/custom order form.

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 0515 Lot 0416
SDS Lot 0416 Lot 0515
PDS Animal-Free Lot 0716 Lot 0716
SDS Animal-Free Lot 0515 Animal-Free  
  Lot 0416 Animal-Free  
  Lot 0716 Animal-Free  

 

 

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