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Canine IL-2

Animal-Free (AF) proteins are identical to regular proteins and include additional documentation that they were produced using ANIMAL-FREE PROCESSES and contain only ANIMAL-FREE RAW MATERIALS.  Learn more HERE.

SKU Select size Price Buy
400-11-5ug Mini: 5 ug $60.00  
400-11-25ug Std.: 25 ug $150.00  
400-11-100ug Value: 100 ug $590.00  
400-11-500ug Midgi: 500 ug $1950.00  
400-11-1mg Mg: 1 mg $3500.00  
400-11AF-5ug Animal-Free Mini: 5 ug $65.00  
400-11AF-25ug Animal-Free Std.: 25 ug $165.00  
400-11AF-100ug Animal-Free Value: 100 ug $650.00  
400-11AF-500ug Animal-Free Midgi: 500 ug $2145.00  
400-11AF-1mg Animal-Free Mg: 1 mg $3850.00  
View the available lots and COAs for this product HERE

Catalog Number:  400-11 and 400-11AF
               

Product Description
Alternate Names:  T cell growth factor, TCGF, Aldesleukin                  Accession Number: Q29416   
Description:  Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes.  IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation.  IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages. 
Source:  Genetically modified E.coli
Predicted MW:  Monomer, 15.6 kDa (with 136 amino acids)
AA Sequence:  MAPITSSSTK ETEQQMEQLL LDLQLLLNGV NNYENPQLSR MLTFKFYTPK KATEFTHLQC LAEELKNLEE VLGLPQSKNV HLTDTKELIS NMNVTLLKLK GSETSYNCEY DDETATITEF LNKWITFSQS IFSTLT
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 20 mM sodium bicarbonate,     pH 8.5

Product Specifications*
*Lot-specific values for the following specifications are supplied with each production lot on its corresponding COA. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS-PAGE

≥95%

Endotoxin

Kinetic LAL (50% confidence)

≤ 1 EUs/µg

Biological Activity

CTLL-2 cell proliferation

ED50 ≤ 5 ng/mL (≥ 2.0 x 10^5 units/mg)


Product Preparation and Storage
Country of Origin:  USA         Shipping:  Room temperature              
Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile 10 mM sodium bicarbonate, pH 8.5 at 0.1 mg/mL       

Instructions:  Centrifuge vial before opening.  Suspend the product by gently pipetting the above recommended solution down the sides of the vial.  DO NOT VORTEX.  Allow several minutes for complete reconstitution.  For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.   


Expiration Date:                      

12 months from date of receipt when stored at -20°C to -80°C as supplied. 

1 month when stored at 4°C after reconstituting as directed.

3 months when stored at -20°C to -80°C after reconstituting as directed.

                                                                                   

THIS PRODUCT IS FOR RESEARCH USE ONLY AND IS NOT FOR USE IN HUMANS!           

 

Data Sheet (PDF)

SDS Document (PDF)

Animal-Free Documents:

Data Sheet AF (PDF)

SDS Document AF (PDF)

To receive more information or a quote, complete our bulk/custom order form.

  • Select size
    Mini: 5 ug, Std.: 25 ug, Value: 100 ug, Midgi: 500 ug, Mg: 1 mg, Animal-Free Mini: 5 ug, Animal-Free Std.: 25 ug, Animal-Free Value: 100 ug, Animal-Free Midgi: 500 ug, Animal-Free Mg: 1 mg