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Rat IL-3 (beta)

Interleukin 3 beta (IL-3 β) is a cytokine that is produced by activated T cells and mast cells.  IL-3 β induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cells.  IL-3 β also functions in the nervous system and is important during the B-1 cell regulation of chronic inflammatory diseases. 

SKU Select size Price Buy
300-39-5UG Mini: 5 ug $63.00 + -
300-39-25UG Std.: 25 ug $158.00 + -
300-39-100UG Value: 100 ug $394.00 + -
300-39-500UG Midgi: 500 ug $1,701.00 + -
300-39-1MG Mg: 1 mg $2,835.00 + -
300-39AF-5UG Animal-Free Mini: 5 ug $69.00 + -
300-39AF-25UG Animal-Free Std.: 25 ug $174.00 + -
300-39AF-100UG Animal-Free Value: 100 ug $436.00 + -
300-39AF-500UG Animal-Free Midgi: 500 ug $1,869.00 + -
300-39AF-1MG Animal-Free Mg: 1 mg $3,119.00 + -
Alternate Names:  MCGF, Multi-CSF, HCGF, P-cell stimulating factor                        
Accession Number: P04823           
Description:  Interleukin 3 beta (IL-3 β) is a cytokine that is produced by activated T cells and mast cells.  IL-3 β induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cells.  IL-3 β also functions in the nervous system and is important during the B-1 cell regulation of chronic inflammatory diseases. 
Source:  Genetically modified E.coli
Predicted MW:  Monomer, 16.3 kDa (with 144 amino acids)
AA Sequence:  MISDRGSDAH HLLRTLDCRT IALEILVKLP YPQVSGLNNS DDKANLRNST LRRVNLDEFL KSQEEFDSQD TTDIKSKLQK LKCCIPAAAS DSVLPGVYNK DLDDFKKKLR FYVIHLKDLQ PVSVSRPPQP TSSSDNFRPM TVEC
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Product Specifications*
*Lot-specific values for the following specifications are supplied with each production lot on its corresponding COA. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS-PAGE

≥ 95%

Endotoxin

Kinetic LAL (50% confidence)

≤ 1 EUs/µg

Biological Activity

NFS-60 cell proliferation

ED50 ≤ 10 ng/mL 

Preparation and Storage

Country of Origin:  USA         Shipping:  Room temperature              
Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL    
Instructions:  Centrifuge vial before opening.  Suspend the product by gently pipetting the above recommended solution down the sides of the vial.  DO NOT VORTEX.  Allow several minutes for complete reconstitution.  For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.   


Expiration Date                       

12 months from date of receipt when stored at -20°C to -80°C as supplied. 

1 month when stored at 4°C after reconstituting as directed.

3 months when stored at -20°C to -80°C after reconstituting as directed.

                                                                                   

THIS PRODUCT IS FOR RESEARCH USE ONLY AND IS NOT FOR USE IN HUMANS!           

 

To receive more information or for a bulk quote, email us at quotes@shenandoah-bt.com.

 

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 1116 Lot 1116
SDS Lot 1116 Animal-Free  
PDS Animal-Free    
SDS Animal-Free