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Porcine FLT-3 Ligand

Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation.  FLT-3 ligand signaling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor.  FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the presence of interleukin 7 (IL-7) or in combination of IL-7 and interleukin 3 (IL-3). 

SKU Select size Price Buy
400-08-5ug Mini: 5 ug $63.00 + -
400-08-25ug Std.: 25 ug $158.00 + -
400-08-100ug Value: 100 ug $578.00 + -
400-08-500ug Midgi: 500 ug $2,310.00 + -
400-08-1mg Mg: 1 mg $3,696.00 + -
400-08AF-5ug Animal-Free Mini: 5 ug $69.00 + -
400-08AF-25ug Animal-Free Std.: 25 ug $174.00 + -
400-08AF-100ug Animal-Free Value: 100 ug $667.00 + -
400-08AF-500ug Animal-Free Midgi: 500 ug $2,657.00 + -
400-08AF-1mg Animal-Free Mg: 1 mg $4,253.00 + -

Alternate Names:  Flt3L, Fms-related tyrosine kinase 3 ligand             

Accession Number: D2K7D6  
Description:  Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation.  FLT-3 ligand signaling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor.  FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the presence of interleukin 7 (IL-7) or in combination of IL-7 and interleukin 3 (IL-3). 
Source:  Genetically modified E.coli
Predicted MW:  Monomer, 17.3 kDa (with 155 amino acids)
AA Sequence:  MSPDCSFPHS PISSTFANTI RQLSDYLLQD YPVTVASNLQ DDELCGAFWR LVLAQRWMGQ LKTVAGSQMQ KLLEAVNTEI VFVTSCALQP LPSCLRFVQA NISHLLQDTS QQLVALKPWI TRRNFSRCLE LQCQPDPSTL LPPRSPGALE ATSLP
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5

Product Specifications*
*Lot-specific values for the following specifications are supplied with each production lot on its corresponding COA. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS-PAGE

≥ 95%

Endotoxin

Kinetic LAL (50% confidence)

≤ 1 EUs/µg

Biological Activity

OCI-AML5 cell proliferation

ED50 ≤ 5 ng/mL 


Preparation and Storage
Country of Origin:  USA         Shipping:  Room temperature              
Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL    
Instructions:  Centrifuge vial before opening.  Suspend the product by gently pipetting the above recommended solution down the sides of the vial.  DO NOT VORTEX.  Allow several minutes for complete reconstitution.  For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.   


Expiration Date                       

12 months from date of receipt when stored at -20°C to -80°C as supplied. 

1 month when stored at 4°C after reconstituting as directed.

3 months when stored at -20°C to -80°C after reconstituting as directed.                                                                           

THIS PRODUCT IS FOR RESEARCH USE ONLY AND IS NOT FOR USE IN HUMANS!           

To receive more information or for a bulk quote, email us at quotes@shenandoah-bt.com.

 

Product Datasheets Certificates of Analysis
PDS Lot 0817
SDS Lot 0817 Animal-Free
PDS Animal-Free  
SDS Animal-Free