Rat VEGF-165

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways.

SKU Select size Price Buy
300-31-2ug Mini: 2 ug $63.00 + -
300-31-10ug Std.: 10 ug $158.00 + -
300-31-100ug Value: 100 ug $457.00 + -
300-31-500ug Midgi: 500 ug $2,268.00 + -
300-31-1mg Mg: 1 $3,780.00 + -
300-31AF-2ug Animal-Free Mini: 2 ug $69.00 + -
300-31AF-10ug Animal-Free Std: 10 ug $174.00 + -
300-31AF-100ug Animal-Free Value: 100 ug $499.00 + -
300-31AF-500ug Animal-Free Midgi: 500 ug $2,494.00 + -
300-31AF-1mg Animal-Free Mg: 1 $4,158.00 + -
Alternate Names:  VEGF-A, VPF, glioma-derived endothelial cell mitogen              
Accession Number: P16612-2
Description:  Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.
Source:  Genetically modified E.coli.
Predicted MW: Dimer, 19.4/38.8 kDa (165/330 aa)
AA Sequence:  MAPTTEGEQK AHEVVKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNVTMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

HUVEC proliferation

ED50 ≤ 8 ng/mL

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             

Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date                      
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

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Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 0716 Lot 0716
SDS Lot 0716 Animal-Free  
PDS Animal-Free    
SDS Animal-Free    
Papers that cite this product:
 

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