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Mouse SDF-1 alpha / CXCL12

SKU Select size Price Buy
200-46-2ug Mini: 2 ug $60.00  
200-46-10ug Std.: 10 ug $150.00  
200-46-100ug Value: 100 ug $375.00  
200-46-500ug Midgi: 500 ug $1620.00  
200-46-1mg Mg: 1 $2700.00  
View the available lots and COAs for this product HERE

Catalog Number: 200-46

Alternate Names:  CXCL12, PBSF               Accession Number: Q4FJL5
Description:  Stromal cell-derived factor-1 alpha (SDF-1 α), also called CXCL12a, is one of two SDF-1 splice variants made by a wide variety of cells upon stimulation by inflammatory cytokines such as TNF, IL-1, and LPS. SDF-1α signals through the G protein-coupled receptor CXCR4 to recruit activated leukocytes. Human and mouse SDF-1 α share 99% sequence identity.
Source:  Genetically modified E.coli.
Predicted MW: Monomer, 8 kDa (68 aa) ***Under non-reducing conditions, samples prepared at higher working concentrations are shown to produce a band of approximately 16 kDa on an SDS PAGE gel, which may represent dimer formation.
AA Sequence:  KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

Bioactive protein, but no acceptance criteria established

≤Currently undetermined; ≥ NA

 

In addition to the acceptance criteria, this product has been tested with the following assay: (1)  Primary human T cell chemotaxis (first detectable at 5-50 ng/mL)

 Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature              Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date:                      
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

Data Sheet (PDF)

SDS Document (PDF)

Papers that use this product (PMID):
23935208

27473763

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  • Select size
    Mini: 2 ug, Std.: 10 ug, Value: 100 ug, Midgi: 500 ug, Mg: 1