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Mouse IL-2

The Animal-Free version of Mouse IL-2 is on back order. 
Estimated availability is Feb 2019.

SKU Select size Price Buy
200-17-5ug Mini: 5 ug $60.00  
200-17-20ug Std.: 20 ug $150.00  
200-17-100ug Value: 100 ug $375.00  
200-17-500ug Midgi: 500 ug $1500.00  
200-17-1mg Mg: 1 mg $2500.00  
View the available lots and COAs for this product HERE

Catalog Number: 200-17 and 200-17AF

Alternate Names:  T cell growth factor, TCGF, Aldesleukin               Accession Number: P04351
Description:  Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes.  IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages.
Source:  Genetically modified E.coli.
Predicted MW: Monomer, 17.4 kDa (150 aa)
AA Sequence:  MAPTSSSTSS STAEAQQQQQ QQQQQQQHLE QLLMDLQELL SRMENYRNLK LPRMLTFKFY LPKQATELKD LQCLEDELGP LRHVLDLTQS KSFQLEDAEN FISNIRVTVV KLKGSDNTFE CQFDDESATV VDFLRRWIAF CQSIISTSPQ
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium citrate, pH 4.0

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

CTLL-2 cell proliferation

≤5 ng/mL; ≥ 2.0 x 10^5 units/mg

 

*** International Units: The specific activity of Mouse IL-2 is approximately 1.14 x 10^5 IU/μg, which is calibrated against recombinant mouse IL-2 WHO International Standard (NIBSC code: 93/566).

 Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature              Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile 10 mM acetic acid at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date:                      
12 months from date of receipt when stored at -20°C to -80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

Data Sheet (PDF)

SDS Document (PDF)

Animal-Free Documents:

Data Sheet AF (PDF)

SDS Document AF (PDF)

Papers that use this product (PMID):
23616302
 
 

To receive more information or a quote, complete our bulk/custom order form.

  • Select size
    Mini: 5 ug, Std.: 20 ug, Value: 100 ug, Midgi: 500 ug, Mg: 1 mg, Animal-Free Mini: 5 ug, Animal-Free Std.: 20 ug, Animal-Free Value: 100 ug, Animal-Free Midgi: 500 ug, Animal-Free Mg: 1 mg