Mouse IL-11 Gel
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Mouse IL-11

Animal-Free (AF) proteins are identical to regular proteins and include additional documentation showing that they were produced with no materials of animal or human origin using ANIMAL-FREE purification processes.  Learn more HERE.

SKU Select size Price Buy
200-64-2ug Mini: 2 ug $63.00 + -
200-64-10ug Std.: 10 ug $158.00 + -
200-64-100ug Value: 100 ug $609.00 + -
200-64-500ug Midgi: 500 ug $3024.00 + -
200-64-1mg Mg: 1 mg $5040.00 + -
200-64AF-2ug Animal-Free Mini: 2 ug $69.00 + -
200-64AF-10ug Animal-Free Std.: 10 ug $174.00 + -
200-64AF-100ug Animal-Free Value: 100 ug $667.00 + -
200-64AF-500ug Animal-Free Midgi: 500 ug $3329.00 + -
200-64AF-1mg Animal-Free Mg: 1 mg $5544.00 + -
  • Weight
    0.0100 lbs
  • SKU
    200-64-2ug
Alternate Names:  AGIF (Adipogenesis Inhibitory Factor), oprelvekin              
Accession Number: P47873
Description:  Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling.
Source:  Genetically modified E.coli.
Predicted MW: Monomer, 19.3 kDa (179 aa)
AA Sequence:  MPGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPADGDH SLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW LRRAGGPSLK TLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGS IRAAHAILGG LHLTLDWAVR GLLLLKTRL
Formulation:  Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Product Specifications*
*Lot-specific values for the following specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specification

Method of Determination

Acceptance Criteria

Purity

Reducing and Non-Reducing SDS PAGE

≥95%

Endotoxin

Kinetic LAL

≤1 EUs/µg

Biological Activity

B9 cell proliferation

ED50 ≤ 250 ng/mL (≥ 4.0 x 10^3 units/mg)

 In addition to the acceptance criteria, this product has been tested with the following assay: 
(1) T-11 proliferation (ED50 ≤ 2.5 ng/mL; ≥ 4.0 x 10^5 units/mg)

Preparation and Storage
Country of Origin:  USA        Shipping:  Room temperature             
Storage Prior to Reconstitution:  -20°C
Product Reconstitution:  Sterile water at 0.1 mg/mL
Instructions:  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Expiration Date                      
12 months from date of receipt when stored at -20°C to-80°C as supplied.
1 month when stored at 4°C after reconstituting as directed.
3 months when stored at -20°C to -80°C after reconstituting as directed.

To receive more information or a quote, complete our bulk/custom order form.

 

Product Datasheets Certificates of Analysis Certificates of Origin
PDS Lot 1217 Lot 1217
SDS Lot 0909  
PDS Animal-Free Lot 1217 Animal-Free  
SDS Animal-Free    

 

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    • $63.00