Human Monocyte/DC Protein Bundle (GM-CSF/IL-4)
Zoom image

Human Monocyte/DC Protein Bundle (GM-CSF/IL-4)

Cytokines for cell culture of dendritic cells from monocytes.  

Bundle includes:
100 ug of Human IL-4
100 ug of Human GM-CSF
(20% savings from individual prices totaling $765)

  • $641.00
Qty:  
  • SKU
    PB-500-01

Dendrictic cells are an important type of immune cell that function to activate T and B cells via their role as an antigen presenting cells.  Monocytes isolated from peripheral blood can be differentiated to immature dendritic cells (iDCs) through culturing in the presence of interleukin 4 (IL-4) and granulocyte-macrophage colony stimulating factor (GM-CSF) for 5-7 days.   The characteristics of monocyte-derived iDCs are detectable after 2 days of culture with IL-4/GM-CSF and include:  the down regulation of CD14 surface expression, an increase in dextran uptake and an increased response to MIP-1a.  Subsequent culturing with pro-inflammatory cytokines (such as TNF-a, IL-1b, and IL-6) can further differentiate the iDCs into mature dendritic cells (mDCs) that have full T cell stimulating capacity. This bundle includes 1x 100 ug vial of Human IL-4 and 1x 100 ug Human GM-CSF. Dependent on user formulation, there is approximately enough IL-4 and GM-CSF to make 2 L of differentiation media.  Specific concentrations of each chemokine are determined by the end user based on their application and culture conditions.

Size: 1 bundle

If this pre-made bundle doesn't fit your needs, complete our bulk/custom order form for a Build Your Own Bundle discount quote (discount depends on quantity and volume).

 

Product Datasheets
PDS
SDS Human GM-CSF
SDS Human IL-4

 

Related products
Search Tip: To help narrow down your search results try:

  • Search product name, no species.
  • Select 'Exact phrase' match
If you're unable to find what you are looking for please contact us.
Drop items here to shop
Product has been added to your cart
  • Drag and drop me to the cart
    • $63.00
  • Drag and drop me to the cart
    • $63.00
  • Drag and drop me to the cart
    • $63.00
  • Drag and drop me to the cart
    • $63.00
  • Drag and drop me to the cart
    • $63.00